Forensically relevant SNP classes.

Allele frequencies for 40 autosomal SNP loci typed for US population samples using electrospray ionization mass spectrometry

AIM To type a set of 194 US African American, Caucasian, and Hispanic samples (self-declared ancestry) for 40 autosomal single nucleotide polymorphism (SNP) markers intended for human identification purposes. METHODS Genotyping was performed on an automated commercial electrospray ionization time-of-flight mass spectrometer, the PLEX-ID. The 40 SNP markers were amplified in eight unique 5plex...

An evidence based strategy for normalization of quantitative PCR data from miRNA expression analysis in forensically relevant body fluids.

Micro-RNA (miRNA) based analysis of body fluids and composition of complex crime stains has recently been introduced as a potential and powerful tool to forensic genetics. Analysis of miRNA has several advantages over mRNA but reliable miRNA detection and quantification using quantitative PCR requires a solid and forensically relevant normalization strategy. In our study we evaluated a panel of...

The Effects of Forensically Relevant Face Coverings on the Acoustic Properties of Fricatives

Typing of 67 SNP Loci on X Chromosome by PCR and MALDI - TOF MS

A set of single nucleotide polymorphisms (SNP) on X chromosome was selected with the aim of forensic identification in Chinese Han population to complement the analysis of autosomal, Y-chromosomal or mitochondrial markers, especially in deficiency cases. 67 forensically relevant X-SNPs were screened in a Chinese Han population sample. Genomic DNA samples extracted from 295 unrelated Chinese Han...

An evidence based strategy for normalization of quantitative PCR data from miRNA expression analysis in forensic organ tissue identification.

Messenger-RNA (mRNA)-based analysis of organ tissues and their differentiation in complex crime stains has recently been introduced as a potential and powerful tool to forensic genetics. Given the notoriously low quality of many forensic samples it seems advisable, though, to substitute mRNA with micro-RNA (miRNA) which is much less susceptible to degradation. However, reliable miRNA detection ...